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Serological and molecular characterization of plasma samples. Individual plasma samples reactivity with Wiener Chagatest ELISA ( A ), Hemagen <t>Chagas</t> ELISA ( B ) and parasite burden measured by qPCR ( C ). Samples were classified as negative (Neg), positive (Pos), or discordant (Disc) based on serological and molecular assays and are color-coded based on country of origin. There was no significant difference in parasite burden between positive and discordant samples ( t = 1.09; P = 0.29). The dotted line in A and B indicates the cut-off for reactive samples
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Serological and molecular characterization of plasma samples. Individual plasma samples reactivity with Wiener Chagatest ELISA ( A ), Hemagen <t>Chagas</t> ELISA ( B ) and parasite burden measured by qPCR ( C ). Samples were classified as negative (Neg), positive (Pos), or discordant (Disc) based on serological and molecular assays and are color-coded based on country of origin. There was no significant difference in parasite burden between positive and discordant samples ( t = 1.09; P = 0.29). The dotted line in A and B indicates the cut-off for reactive samples
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Image Search Results


Journal: Critical Care and Resuscitation

Article Title: An in-vitro study to characterise analytical interference caused by sodium ascorbate with point-of-care measurement of lactate and glucose

doi: 10.1016/j.ccrj.2026.100174

Figure Lengend Snippet: Measurements for lactate and blood glucose across devices.

Article Snippet: Baseline and spiked blood samples were immediately analysed at the bedside with several POC devices, based on availability, including the RAPIDPoint® 500 Blood gas system (Siemens HealthCare, Erlangen, Germany), Epoc® Blood analysis system (Siemens HeathCare, Erlangen, Germany), Radiometer ABL800 blood gas analyser (Radiometer, Copenhagen, Denmark), StatProfile® Prime Plus blood gas analyser (Nova Biomedical, Waltham, USA), i-STAT 1® blood analyser (Abbott Laboratories, North Chicago, USA), HemoCue® Glucose 201 (HemoCue, Angelholm, Sweden), FreeStyle Optium Neo (Abbott, Illinois, USA), StatStrip Xpress® lactate system (Nova Biomedical, Waltham, USA) and the StatStrip Xpress® glucose meter (Nova Biomedical, Waltham, USA) ( ).

Techniques:

Measured lactate at baseline and target ascorbate levels for ABL800, Prime Plus, Roche colorimetric (SA Pathology), Epoc, StatStrip Xpress, and i-STAT 1 blood analyser (in series order). Data are median [IQR].

Journal: Critical Care and Resuscitation

Article Title: An in-vitro study to characterise analytical interference caused by sodium ascorbate with point-of-care measurement of lactate and glucose

doi: 10.1016/j.ccrj.2026.100174

Figure Lengend Snippet: Measured lactate at baseline and target ascorbate levels for ABL800, Prime Plus, Roche colorimetric (SA Pathology), Epoc, StatStrip Xpress, and i-STAT 1 blood analyser (in series order). Data are median [IQR].

Article Snippet: Baseline and spiked blood samples were immediately analysed at the bedside with several POC devices, based on availability, including the RAPIDPoint® 500 Blood gas system (Siemens HealthCare, Erlangen, Germany), Epoc® Blood analysis system (Siemens HeathCare, Erlangen, Germany), Radiometer ABL800 blood gas analyser (Radiometer, Copenhagen, Denmark), StatProfile® Prime Plus blood gas analyser (Nova Biomedical, Waltham, USA), i-STAT 1® blood analyser (Abbott Laboratories, North Chicago, USA), HemoCue® Glucose 201 (HemoCue, Angelholm, Sweden), FreeStyle Optium Neo (Abbott, Illinois, USA), StatStrip Xpress® lactate system (Nova Biomedical, Waltham, USA) and the StatStrip Xpress® glucose meter (Nova Biomedical, Waltham, USA) ( ).

Techniques:

Serological and molecular characterization of plasma samples. Individual plasma samples reactivity with Wiener Chagatest ELISA ( A ), Hemagen Chagas ELISA ( B ) and parasite burden measured by qPCR ( C ). Samples were classified as negative (Neg), positive (Pos), or discordant (Disc) based on serological and molecular assays and are color-coded based on country of origin. There was no significant difference in parasite burden between positive and discordant samples ( t = 1.09; P = 0.29). The dotted line in A and B indicates the cut-off for reactive samples

Journal: Medical Microbiology and Immunology

Article Title: Epitope mapping and conservation of antigens from the Multi-Cruzi immunoassay platform

doi: 10.1007/s00430-026-00877-z

Figure Lengend Snippet: Serological and molecular characterization of plasma samples. Individual plasma samples reactivity with Wiener Chagatest ELISA ( A ), Hemagen Chagas ELISA ( B ) and parasite burden measured by qPCR ( C ). Samples were classified as negative (Neg), positive (Pos), or discordant (Disc) based on serological and molecular assays and are color-coded based on country of origin. There was no significant difference in parasite burden between positive and discordant samples ( t = 1.09; P = 0.29). The dotted line in A and B indicates the cut-off for reactive samples

Article Snippet: These samples had been tested with Chagas STAT PAK ® (Chembio Diagnostic, Inc.), Trypanosoma DetectTM (InBios), Chagatest ELISA recombinant v.3.0 (Wiener), and Hemagen ® Chagas’ Kit (Hemagen) as well as by quantitative real time PCR and two end-point PCR assays, one targeting nuclear satellite DNA (primers TcZ1-TcZ2) [ ], and one targeting minicircle DNA (primers 121–122) [ ], with extensive quality control and cross-validation among participating laboratories [ , ].

Techniques: Clinical Proteomics, Enzyme-linked Immunosorbent Assay